ABSTRACT
Oral health can be a good indicator of general health and has been linked to systemic diseases, therefore, maintaining good oral hygiene is important. Oral infections are polymicrobial with dental caries and periodontal disease being the major oral conditions affecting the public. A retrospective study on patients with orodontal conditions in the dental clinic of Ahmadu Bello University Medical Centre, Zaria between January 1st , 2015 and December 31st, 2017 was performed. The medical records of patients diagnosed to have dental conditions were collated. Also prospective study assessed the prevalence of antimicrobial resistance among the common bacterial isolates associated with periodontal disease from oral rinses of patients in the clinic (3months) using standard microbiological methods. The antibiotic susceptibility pattern of bacterial isolates was evaluated using the European Committee on Antimicrobial Susceptibility Testing 2018 recommended guidelines. Data analysis was carried out using descriptive statistics and Chi-square tests was used to determine the significant differences (P<0.05) where appropriate. Out of 10364 visits, prevalence of periodontal disease (65.8%) and dental carries (34.2%) was observed with a significant difference of (P=0.000). A high percentage of male patients 60.5% was observed compared to female patients 39.5% with a significant difference of (P=0.004) was recorded. Most predominate patients were adults. A total of 131 samples of patients with dental conditions was collected with about 40 anaerobic Gram negative bacteria isolated. Prevotella intermedia (18%) and Bacteriode fragilis (18%) were the most frequently isolated bacteria, followed by Fusobacterium nucleatum (10%), Fusobacterium varidium and Prevotella oralis (8%) and Fusobacterium mortiferum, Bacteriode stercoris and Porphyromonas asaccharolytica (6%). High resistance of isolated bacteria to selected antibiotics was observed in metronidazole and chloramphenicol (100%) and amoxicillin-clavulanic acid ix (62.5%). About 77.5% of the bacteria isolates were biofilm producers and 22.5% nonbiofilm producers. Nine of the anaerobic Gram negative bacteria isolates were characterized genotypically. The resistance gene blaTEM was observed in only one bacterial isolate while cat gene was conserved in all the nine isolates characterized genotipically. The nim gene was virtually absent. This study showed a high prevalence of oral disease among tested patients with adults and male gender preponderance. The antimicrobial resistance rates observed was high and may pose a serious therapeutic challenge to the management of periodontal disease. Preventive measures and sustainable therapeutic strategies for oral health services advocated.
ABSTRACT
The history of oil exploration and production in the Niger Delta is a long, complex and often...
ABSTRACT
Data mining is the extraction of hidden predictive information from large database which helps in predicting future trend and be...
BACKGROUND OF THE STUDY
The expansion of the labor sector always needs a defined connection between uni...
ABSTRACT
The aim of this research is to address the impact and implications of social media on the Nigerian youth e...
ABSTRACT
Climate change is now generally recognized as the greatest challenge to sustainable developmen...
ABSTRACT
A company will have stated objectives, but the individual manager must interpret what company officials actually say and do. For...
Background of the study
His of Soymilk: Soybeans belongs to the family leguminous, subfamily papiliondase and the genus...
ABSTRACT
This study was carried out to examine how to prevent computer system infection and compromise using trojan...
ABSTRACT
Federal Ministry of Finance has always monitoring how ec...
ABSTRACT
It is a known fact that Discourse Analysis is the analysis of language in use. This work showed how discourse analysis and pragm...